49ers Confirm Mac Jones to Start Again as Brock Purdy Remains Out — Ricky Pearsall Officially Ruled Out vs. Buccaneers.CRISS

Santa Clara, CA – October 11, 2025

The San Francisco 49ers are preparing for another week without their starting quarterback. Head coach Kyle Shanahan confirmed that Mac Jones will once again start in place of

Brock Purdy, who remains sidelined with a lingering turf toe injury on his right foot. The 49ers are set to face the Tampa Bay Buccaneers in Week 6.

Purdy, who missed last week’s overtime win against the Los Angeles Rams, has made progress but is still not ready for game action. The team hopes to have him back by Week 7 if recovery continues as planned. His absence means Jones will get a second straight opportunity to command the offense — a chance to further prove his growth since joining the team this offseason.

Jones played efficiently in his first start, completing 21 of 30 passes for 212 yards and a touchdown. Despite minor discomfort in his oblique and knee, Shanahan said the quarterback

“looked composed and made good decisions,” and that he earned another week as the starter.

The 49ers will, however, be without rookie wide receiver Ricky Pearsall, who was ruled out with a knee injury suffered during Wednesday’s practice. His absence could open more opportunities for Jauan Jennings and Danny Gray, with Deebo Samuel and Brandon Aiyuk expected to shoulder a heavier workload in the passing game.

San Francisco’s offensive depth has been tested all season, with injuries across multiple positions, but the coaching staff remains confident in the group’s resilience. “It’s next man up — that’s how this team operates,”

Shanahan said. “We trust whoever steps on that field.”

 

As the 49ers aim to improve their 4–1 record, the spotlight now turns to Jones, who has a chance to solidify his place as one of the league’s most dependable backup quarterbacks — and perhaps spark new competition at the position once Purdy returns.

Stay tuned to ESPN!

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